ReviewInternational journal of burns and trauma2026
Cardiac biomarkers in acute burn injury: a systematic review of diagnostic and prognostic utility.
Review in International journal of burns and trauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCardiac biomarkers offer potential for early diagnosis and prognosis; however, their utility in burn care is not well established. This systematic review aimed to evaluate the current evidence regarding the diagnostic and prognostic values of cardiac biomarkers in patients with acute burn injuries.
methodsA systematic search of PubMed and Google Scholar (July 2015-September 2025) was conducted according to the PRISMA guidelines. We included prospective and retrospective observational studies that evaluated troponin (I or T), B-type natriuretic peptide (BNP), or N-terminal pro-BNP (NT-proBNP) in patients with acute burns and reported clinical outcomes. Case reports, reviews, and studies of patients with pre-existing cardiovascular diseases were excluded.
resultsSeven original studies were included in this systematic review. The findings consistently demonstrated that elevated troponin levels were associated with larger burn sizes, sepsis, and increased mortality, reflecting systemic stress rather than primary ischemic events. BNP and NT-proBNP levels are strong independent predictors of mortality, sepsis, and toxic myocarditis. Notably, BNP demonstrated superior sensitivity to troponin for the early detection of myocarditis in patients with moderate-to-severe burns.
conclusionsCardiac biomarkers are valuable prognostic indicators in acute burn injuries, strongly associated with mortality and major complications. The integration of these factors into clinical practice could significantly enhance early risk stratification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.