Evidence map›Paper›PMID 42787356›Full record

ArticleOpen forum infectious diseases2026

Source Control in

Antonio Vena, Martina Bavastro, Marco Muccio, Michela Schenone, Silvia Corcione, Renato Pascale, Daniele Roberto Giacobbe, Simone Mornese Pinna, Bianca Pari, Francesca Giovannenze and 16 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Antonio VenaDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.ORCID https://orcid.org/0000-0002-0697-3992
Martina BavastroDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Marco MuccioClinica Malattie Infettive, AOM - IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID https://orcid.org/0009-0004-0297-1019
Michela SchenoneClinica Malattie Infettive, AOM - IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Silvia CorcioneDepartment of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
Renato PascaleInfectious Diseases Unit, IRCCS-Sant' Orsola Polyclinic, Bologna, Italy.
Daniele Roberto GiacobbeDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Simone Mornese PinnaDepartment of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
Bianca PariDepartment of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
Francesca GiovannenzeDepartment of Laboratory and Infectious Sciences, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy.
Nicholas GeremiaUnit of Infectious Diseases, Department of Clinical Medicine, Dell'Angelo Hospital, Venice, Italy.ORCID https://orcid.org/0000-0001-7988-5419
Malgorzata MikulskaDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Eleonora TaddeiDepartment of Laboratory and Infectious Sciences, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy.
Flavio SangiorgiDepartment of Security and Bioethics-Infectious Diseases Section, Catholic University of the Sacred Heart, Rome, Italy.
Davide Fiore BavaroDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Vincenzo ScaglioneInfectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy.ORCID https://orcid.org/0000-0002-2911-2255
Silvia SistoDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Lucia TaramassoClinica Malattie Infettive, AOM - IRCCS Ospedale Policlinico San Martino, Genoa, Italy.ORCID https://orcid.org/0000-0002-6622-6358
Veronica VassiaInfectious and Tropical Disease Unit, Mauriziano Umberto I Hospital, Turin, Italy.ORCID https://orcid.org/0000-0002-7097-0710
Michele BartolettiDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Francesco Giuseppe De RosaDepartment of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
Maddalena GiannellaInfectious Diseases Unit, IRCCS-Sant' Orsola Polyclinic, Bologna, Italy.
Pierluigi VialeInfectious Diseases Unit, IRCCS-Sant' Orsola Polyclinic, Bologna, Italy.ORCID https://orcid.org/0000-0003-1264-0008
Matteo BassettiDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
SITA GIOVANI (Young Investigators Group of the Società Italiana Terapia Antinfettiva
SITA GIOVANI (Young Investigators Group of the Società Italiana Terapia Antinfettiva

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Appropriate antibiotic therapy is a key determinant of outcomes in Methods: We conducted a retrospective multicenter study including hospitalized patients with Results: Overall, 639 BSI episodes were analyzed. The most frequent sources were an unknown source (31.8%), central venous catheter BSI (22.5%), hospital-acquired/ventilator-associated pneumonia (20.3%), urinary tract infections (11.4%), and intra-abdominal infections (6.9%). Source control was required in 34.0% of cases and was achieved early and adequately in 49.3% of these. The 30-day all-cause mortality rate was 23.9%. Mortality was significantly lower in patients who received early adequate source control (6.5%) compared with those without early adequate source control (23.6%) or in whom it was deemed unnecessary (28.4%) ( Conclusions: Early adequate source control is a critical determinant of survival in

Indexed as

bloodstream infectionsmortalityPseudomonas aeruginosasource control

Identifiers

PMID42787356
PMCPMC13601804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.