Evidence map›Paper›PMID 42787298›Full record

ArticleCureus2026

Boerhaave Syndrome: Challenges Faced to Achieve Positive Outcomes.

Nikhil Reddy, Sankar Subramaniam, Chinni Vikram Asokan, Suresh Kumar, Dheeraj Kethireddy

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nikhil ReddySurgical Gastroenterology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Sankar SubramaniamSurgical Gastroenterology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Chinni Vikram AsokanSurgical Gastroenterology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Suresh KumarSurgical Gastroenterology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Dheeraj KethireddySurgical Gastroenterology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Boerhaave syndrome, the spontaneous barogenic rupture of the oesophagus, is lethal when unrecognised and its cardiorespiratory mimicry frequently delays diagnosis. Optimal management remains debated. We retrospectively reviewed four consecutive patients with spontaneous oesophageal perforation managed over two years at a tertiary surgical-gastroenterology unit. Diagnosis was confirmed by water-soluble oral-contrast computed tomography; presentation, operative findings, complications and outcomes were analysed and compared with the contemporary literature. The four patients were initially assessed by non-surgical services, with an intercostal drain placed for a presumed effusion or pneumothorax before food or purulent fluid in the drain revealed the diagnosis. The perforation was left-sided in three and right-sided in one. Management was individualised: laparoscopy converted to laparotomy with transhiatal primary repair and omental buttress; laparotomy with transhiatal repair and thoracoscopic lavage; a thoraco-abdominal approach; and a right posterolateral thoracotomy. A postoperative leak occurred in two patients and was managed by endoscopic vacuum therapy and by transhiatal oesophagectomy with gastric conduit, respectively. All four patients survived. Food-stained or purulent output from a chest drain placed for a presumed effusion should prompt immediate contrast computed tomography. An individualised, multidisciplinary strategy combining timely source control, thoracoscopic pleural lavage and modern endoscopic rescue achieved survival in every patient, including a rare right-sided rupture.

Indexed as

boerhaave syndromeendoscopic vacuum therapyoesophageal perforationoesophagectomythoracoscopy

Identifiers

PMID42787298
PMCPMC13601370

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.