ArticleFrontiers in oral health2026
Longitudinal oral and craniofacial follow-up of a genetically confirmed girl with Potocki-Lupski syndrome and repaired complete cleft palate: a case report.
Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Longitudinal data describing the oral and craniofacial development of patients with Potocki-Lupski syndrome (PTLS) are scarce, particularly in individuals with repaired cleft palate. We report the long-term dental and craniofacial follow-up of a genetically confirmed Venezuelan girl with PTLS and repaired complete cleft palate, highlighting the contribution of continuous pediatric dental care within a multidisciplinary craniofacial team. Case report: A girl with repaired complete cleft palate was followed from the neonatal period through the mixed dentition stage, following genetic confirmation of PTLS by chromosomal microarray analysis. Comprehensive multidisciplinary evaluation documented developmental delay, generalized hypotonia, cardiovascular anomalies, gastrointestinal dysfunction, and food sensitizations. Dental management included fabrication of a neonatal palatal obturator, comprehensive preventive care, restorative treatment, orthopedic intervention, and full-mouth rehabilitation under intravenous conscious sedation. Longitudinal clinical and radiographic follow-up demonstrated satisfactory oral health, normal permanent tooth development, mild residual maxillary transverse constriction, a skeletal Class II relationship, and a hyperdivergent craniofacial growth pattern. Conclusion: This case illustrates the complexity of oral and craniofacial development in PTLS associated with repaired complete cleft palate and underscores the value of longitudinal pediatric dental follow-up in documenting growth and guiding clinical management. Continuous dental surveillance integrated within a multidisciplinary team facilitated timely preventive, restorative, and interceptive interventions while supporting long-term oral health and functional rehabilitation. Additional longitudinal studies are needed to define the oral phenotype of PTLS better and strengthen the evidence guiding multidisciplinary care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.