Evidence map›Paper›PMID 42787092›Full record

ArticleIDCases2026

Missed opportunities and near-miss diagnoses in congenital syphilis: A case series of five infants at a tertiary care centre in Nepal.

Srijana Basnet, Luna Bajracharya, Rachana Shrestha, Pradeep Gupta, Prabina Shrestha

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Srijana BasnetDepartment of Pediatrics, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Luna BajracharyaDepartment of Pediatrics, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Rachana ShresthaDepartment of Pediatrics, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Pradeep GuptaDepartment of Pediatrics, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Prabina ShresthaDepartment of Pediatrics, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital syphilis remains a preventable but underrecognized condition in Nepal, where routine antenatal screening is limited to the first visit. We report five infants with diverse clinical manifestations, including hydrops fetalis, bullous lesions, bone involvement, and persistent rhinitis. Four were classified as highly probable and one as possible congenital syphilis according to the 2021 CDC criteria. Four mothers had initially negative screening results, highlighting the possibility of infection acquired later in pregnancy. Due to penicillin unavailability, all infants received ceftriaxone despite limited supporting evidence. The cases emphasize the importance of appropriate repeat maternal testing, follow-up and treatment of seropositive mothers, systematic infant evaluation, and reliable access to penicillin.

Indexed as

Antenatal screeningCeftriaxoneCongenital syphilisRapid plasma reagin

Identifiers

PMID42787092
PMCPMC13601035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.