ArticleJournal of neuroendovascular therapy2026
Telescope-Assisted Combined Thrombectomy (TACT-MeVO) for M2 Occlusion: A Technical Note and Initial Experience.
Article in Journal of neuroendovascular therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
Objective: This study aimed to describe telescope-assisted combined thrombectomy for medium vessel occlusion (TACT-MeVO) in patients with M2 occlusion and report our initial experience. Methods: We retrospectively reviewed 52 thrombectomy procedures in 51 patients with M2 occlusion between May 2015 and April 2026: 45 historical-protocol and 7 TACT-MeVO procedures. In TACT-MeVO, a small-bore aspiration catheter and stent retriever are withdrawn together into a large-bore M1 aspiration catheter. Outcomes and between-group P values were exploratory and descriptive; the study was not powered to test superiority. Results: TACT-MeVO was first-line in all 7 procedures. Baseline CT-Alberta Stroke Program Early CT Score was numerically higher in the TACT-MeVO group but did not differ significantly (P = 0.069). Median puncture-to-recanalization/procedure-end time was 59 vs. 71 min (P = 0.014). One-pass completion was achieved in 6/7 (85.7%) vs. 23/45 procedures (51.1%; P = 0.117), and final modified Thrombolysis in Cerebral Infarction ≥2b in 7/7 (100%) vs. 39/45 procedures (86.7%; P = 0.580). Any subarachnoid hemorrhage occurred in 2/7 vs. 8/45 procedures (P = 0.608); both TACT-MeVO events were asymptomatic. Three-month modified Rankin Scale score 0-2 did not differ significantly (5/7 vs. 16/45; P = 0.104). A post hoc comparison with 29 procedures using conventional combined thrombectomy also showed a shorter procedural time (59 vs. 70 min; P = 0.004). Conclusion: TACT-MeVO was technically feasible in this initial 7-procedure experience. Comparative findings are descriptive; superiority or safety cannot be inferred because of the small sample, baseline imbalance, and historical comparator.
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