ArticleFrontiers in endocrinology2026
Systematic adolescent-centered supportive care program is associated with improved psychological status, treatment adherence, and social adaptation in adolescents with thyroid cancer undergoing radioiodine-131 therapy: a retrospective before-after cohort study with historical controls.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Adolescents and young adults (AYAs) with differentiated thyroid cancer (DTC) undergoing radioiodine-131 ( Methods: We enrolled 220 eligible patients aged 13-25 years with DTC receiving Results: In linear mixed-effects models, the observation group exhibited significantly lower 6-month SAS and SDS scores (all adjusted P < 0.001).Significant group×time interactions for both scales demonstrated sustained psychological improvements. In multivariable logistic regression analyses adjusting for potential confounders, the observation group also achieved superior treatment adherence( Conclusion: A standardized adolescent-centered supportive care program was associated with persistent anxiety and depression relief, improved adherence and social reintegration among AYAs with DTC receiving
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