Evidence map›Paper›PMID 42786515›Full record

ArticleActa veterinaria Scandinavica2026

Equine neuroborreliosis in Scandinavia: cerebrospinal fluid PCR confirmation and successful treatment in a mare.

Sofia Ruiz, Marianne Øverlie, Amanda Bergren, Ingunn Risnes Hellings

Abstract readCase Reports
In one paragraph

Article in Acta veterinaria Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia RuizDobloug & Ruiz Veterinærtjenester AS, Sankt Mikaels Veg 285, Vang På Hedmarken, 2324, Norway. sofiavalenciaruiz10@gmail.com.ORCID https://orcid.org/0009-0005-4441-7443
Marianne ØverlieBjerke Dyrehospital, Refstadveien 1, Oslo, 0589, Norway.
Amanda BergrenBjerke Dyrehospital, Refstadveien 1, Oslo, 0589, Norway.
Ingunn Risnes HellingsDepartment of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Postboks 5003, Ås, 1432, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLyme borreliosis (LB), caused by Borrelia burgdorferi sensu lato, is an emerging concern in human medicine, and is a controversial topic in equine medicine. Neuroborreliosis (NB), a neurologic manifestation of LB, remains challenging to diagnose due to nonspecific clinical signs and the lack of definitive diagnostic methods. This report describes the first documented case of equine NB in Scandinavia. CASE PRESENTATION: An 11-year-old mare presented with progressive weight loss, ataxia, muscle atrophy, and hyperesthesia. Cerebrospinal fluid (CSF) analysis revealed neutrophilic pleocytosis, elevated protein and a positive PCR result for Borrelia spp. The mare showed clinical improvement and long-term recovery following prolonged doxycycline therapy.

conclusionsThis case is the first reported case of neuroborreliosis in a horse in Scandinavia and supports the diagnostic relevance of CSF PCR in conjunction with clinical and cytological findings. It also underscores the potential for recovery in equine NB when early antimicrobial treatment is initiated.

Indexed as

Anti-Bacterial AgentsDoxycyclineHorse DiseasesLyme NeuroborreliosisAnimalsFemaleHorsesPolymerase Chain ReactionScandinavian and Nordic CountriesAnti-Bacterial AgentsDoxycyclineBorreliaCerebrospinal fluidDoxycyclineEquineNeuroinfection

Identifiers

PMID42786515
PMCPMC13613778

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.