Evidence map›Paper›PMID 42785982›Full record

ReviewRenal failure2026

Impact of adsorptive CRRT membranes on vancomycin pharmacokinetics in critically ill patients.

Hongxia Zou, Xiang Li, Qing Xu, Zhifeng Zhou, Lu Jin, Fang Wang, Yingying Yang, Ling Zhang

Abstract readReview
In one paragraph

Review in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongxia ZouDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Xiang LiDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Qing XuDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Zhifeng ZhouDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Lu JinDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Fang WangDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Yingying YangDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.
Ling ZhangDepartment of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous renal replacement therapy (CRRT) is a vital organ support modality for critically ill patients. Adsorptive membranes, particularly AN69ST and oXiris, are increasingly used in clinical practice; however, their impact on the pharmacokinetics of antibiotics with a narrow target concentration range between efficacy and toxicity, such as vancomycin, remains incompletely defined. Considerable heterogeneity exists among available studies. Multiple in vitro dynamic circulation models reported adsorption of 12% to 19.5% of the initial vancomycin dose, whereas some static or open-model

Indexed as

Anti-Bacterial AgentsContinuous Renal Replacement TherapyMembranes, ArtificialVancomycinAdsorptionCritical IllnessDrug MonitoringHumansAnti-Bacterial AgentsMembranes, ArtificialVancomycinadsorptionAN69STContinuous renal replacement therapypharmacokineticstherapeutic drug monitoringvancomycin

Identifiers

PMID42785982
PMCPMC13618156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.