Evidence map›Paper›PMID 42785920›Full record

ArticleJournal for immunotherapy of cancer2026

Toward precision adjuvant immunotherapy in high-risk clear cell renal cell carcinoma: integrating plasma multiomics with PD-1 blockade.

Rakesh Kumar, Duminduni Hewa Angappulige, Jianxun Song

Abstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rakesh KumarDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, Texas, USA.
Duminduni Hewa AngappuligeDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, Texas, USA.
Jianxun SongBiochemistry and Molecular Biology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, Louisiana, USA jianxun.song@lsuhs.edu.ORCID http://orcid.org/0000-0002-9734-6176

Funding

Combating melanoma with an attenuated bacterial therapeuticR01CA273002 · NCI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI Jianxun Jim Song · 2023 to 2026
$1.8M
Integrative Targeted Therapy for MelanomaR01CA282254 · NCI · UNIVERSITY OF KENTUCKY · PI SONG, JIANXUN JIM, YANG, JIN-MING · 2024 to 2025
$1.2M
NCI NIH HHS R01 CA273002NCI NIH HHS R01 CA282254
6 · The paper itself

Abstract

Despite curative-intent nephrectomy, approximately one-third of patients with localized clear cell renal cell carcinoma (ccRCC) eventually experience disease recurrence due to occult minimal residual disease. Although adjuvant immune checkpoint blockade has transformed postoperative management for patients at high risk of relapse, clinical benefit remains heterogeneous, underscoring the need for biomarkers capable of identifying individuals most likely to benefit from treatment. In this issue of the

Indexed as

Carcinoma, Renal CellImmune Checkpoint InhibitorsImmunotherapyKidney NeoplasmsPrecision MedicineProgrammed Cell Death 1 ReceptorBiomarkers, TumorChemotherapy, AdjuvantHumansMultiomicsBiomarkers, TumorImmune Checkpoint InhibitorsProgrammed Cell Death 1 ReceptorAdjuvantImmunotherapy

Identifiers

PMID42785920
PMCPMC13630094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.