Automated Brief Hospital Course Summarization in Cardiac Surgery Using a Lightweight Large Language Model-Based Framework: Development and Evaluation Study on the Medical Information Mart for Intensive Care-IV.

backgroundPhysician documentation requirements are a known contributor to clinician burnout, with the manual creation of brief hospital course (BHC) summaries being particularly time-consuming. Automating BHC summarization may mitigate this workload and reduce documentation errors. However, current natural language processing (NLP) methods are often limited to single-document inputs, and large language models (LLMs) face privacy and deployment challenges. Furthermore, existing methods often require manual information extraction and struggle to maintain temporal accuracy.

objectiveWe developed and evaluated LiteMedDoc, a lightweight, locally deployable LLM-based framework to automatically generate BHC summaries without model fine-tuning. Our objective was to determine whether clinically useful clinical summaries could be generated under strict privacy and resource constraints, making automated summarization feasible in real-world hospital environments.

methodsLiteMedDoc is a modular pipeline built upon an 8-billion-parameter open-source LLM (Llama 3.1). It features 3 specialized modules: a static dynamic information hierarchy module to condense multisource inputs and structure clinical events chronologically; a similar document retrieval-augmented generation module that retrieves contextually relevant prior case summaries; and a self-adaptive feedback optimization module used offline for prompt optimization. All processing was performed locally without any model fine-tuning. We evaluated the framework on a retrospective cohort of 4538 coronary artery bypass grafting (CABG) surgery cases from the Medical Information Mart for Intensive Care (MIMIC)-IV database. A held-out test set of 403 cases was used to generate BHC summaries. The model-generated summaries were compared to reference BHCs using 8 standard NLP metrics covering lexical overlap (BLEU-4 [Bilingual Evaluation Understudy-4 gram] and ROUGE [Recall-Oriented Understudy for Gisting Evaluation]), semantic similarity (BERTScore and METEOR [Metric for Evaluation of Translation With Explicit Ordering]), and clinical relevance (AlignScore [Alignment Score] and MEDCON [Medical Concept Overlap]). Additionally, 15 cardiac surgeons conducted a clinical evaluation of a sample of model-generated summaries, rating them on completeness, correctness, readability, conciseness, and global quality using a 5-point Likert scale.

resultsWithout any model training, LiteMedDoc achieved strong performance across individual automated metrics, nearly matching a fine-tuned model and exceeding a 70-billion-parameter model on all metrics. Additionally, in a within-database cross-domain evaluation on lobectomy cases, the framework maintained encouraging performance after prompt adaptation and outperformed both the base model and the CABG-fine-tuned model. Surgeons rated the AI-generated summaries above the prespecified acceptability threshold across all domains (mean scores ≥3.0), specifically praising their structure and conciseness.

conclusionsBy integrating 3 specialized modules, the proposed framework offers a practical, locally deployable solution for clinician-in-the-loop BHC draft generation under privacy and resource constraints, and holds promise for improving documentation efficiency and enhancing information continuity during care transitions.