SynthesisStem cell reports2026
Quality control and non-clinical testing of iPSC- and ESC-derived medicinal products: A systematic review.
Synthesis in Stem cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lack of specific resources for quality control (QC) and non-clinical testing of cell-based medicinal products derived from embryonic and induced pluripotent stem cells (PSCs) contributes to uncertainty, variability, and delay in devising testing strategies. We conducted a systematic review on testing practices for diverse PSC-derived medicinal products using a custom-made ranking system, compiling a comprehensive "QC menu" of relevant critical quality attributes, established fit-for-purpose and promising techniques, and study designs for product development or clinical release. This consolidated resource could benefit product developers and regulators by creating informative testing strategies, ultimately increasing harmonization, facilitating clinical translation, and ensuring patient safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.