Evidence map›Paper›PMID 42784785›Full record

ArticleJCO global oncology2026

Barriers and Facilitators Influencing National Scaleup of a Women's Cancer Early Detection Program in Rwanda: Perspectives of Policymakers, Program Leaders, and Clinicians.

Jean de Dieu Uwihaye, Lumen Constance Hirwa, Amanda M Fata, Alexandra Fehr, Anne F Rositch, Jean Marie Vianney Dusengimana, Vestine Rugema, Francois Uwinkindi, Theoneste Maniragaba, Marc Hagenimana and 2 more

Abstract read
In one paragraph

Article in JCO global oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jean de Dieu UwihayePartners in Health/Inshuti Mu Buzima, Kigali, Rwanda.
Lumen Constance HirwaBrigham and Women's Hospital, Boston, MA.ORCID 0009-0004-7943-5329
Amanda M FataBrigham and Women's Hospital, Boston, MA.ORCID 0000-0002-9512-1678
Alexandra FehrPartners in Health/Inshuti Mu Buzima, Kigali, Rwanda.ORCID 0000-0002-0147-8044
Anne F RositchJohns Hopkins Bloomberg School of Public Health, Baltimore, MD.ORCID 0000-0002-0403-8482
Jean Marie Vianney DusengimanaPartners in Health/Inshuti Mu Buzima, Kigali, Rwanda.ORCID 0000-0002-3074-1091
Vestine RugemaPartners in Health/Inshuti Mu Buzima, Kigali, Rwanda.ORCID 0000-0001-6846-8142
Francois UwinkindiRwanda Biomedical Center, Kigali, Rwanda.ORCID 0000-0001-8087-8443
Theoneste ManiragabaRwanda Biomedical Center, Kigali, Rwanda.ORCID 0000-0002-0746-3011
Marc HagenimanaRwanda Biomedical Center, Kigali, Rwanda.ORCID 0000-0001-9399-745X
Vincent K CubakaPartners in Health/Inshuti Mu Buzima, Kigali, Rwanda.ORCID 0000-0001-7449-2421
Lydia E PaceBrigham and Women's Hospital, Boston, MA.ORCID 0000-0002-5378-0296

Funding

Evaluating scaleup of an adapted breast cancer early diagnosis program in RwandaR21CA260010 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI PACE, LYDIA · 2022 to 2023
$409k
NCI NIH HHS R21 CA260010
6 · The paper itself

Abstract

purposeLate-stage diagnoses drive high rates of cervical and breast cancer mortality in low- and middle-income countries (LMICs) where early detection efforts are typically small-scale. Rwanda's government-funded Women's Cancer Early Detection Program (WCEDP) integrates breast cancer early detection and cervical cancer screening and is being scaled nationally. We aimed to understand barriers and facilitators of WCEDP scale-up to inform program optimization and provide lessons for other LMICs.

methodsWe conducted 23 in-depth interviews with clinicians, health facility leaders, nongovernmental organization (NGO) staff, and policymakers. A codebook was collaboratively developed using a combined inductive and deductive approach; all transcripts were dual-coded. The Exploration, Preparation, Implementation, and Sustainment (EPIS) framework served as a guiding theoretical framework.

resultsOuter context: WCEDP facilitators include strong government engagement, national cancer control plans, and community acceptance. Barriers include low community awareness and insufficient resources dedicated to the program. Inner context: Rwanda's decentralized health care system and community health workers facilitated WCEDP scale-up. Nonetheless, workforce shortages, limited health facility leadership engagement and accountability, and clinicians' unfamiliarity with electronic health records (EHRs) were challenges. Innovation factors: The WCEDP-specific EHR was considered a strength. However, participants identified the need for training, technical assistance, ongoing quality monitoring, and adaptation to effectively use the EHR to improve care delivery and link patients to follow-up. Bridging factors: NGOs play a key role in WCEDP implementation. However, participants reported a need for improved coordination of different stakeholders. Phases of implementation: Identified facilitators and barriers provided lessons relevant to all EPIS phases (Exploration, Preparation, Implementation, and Sustainment).

conclusionThis study contributes to the limited literature examining scale-up of cancer programs in resource-constrained settings and informs strategies to optimize women's cancer early detection at scale in Rwanda and other LMICs.

Indexed as

Breast NeoplasmsEarly Detection of CancerUterine Cervical NeoplasmsAdministrative PersonnelFemaleHumansLeadershipResource-Limited SettingsRwanda

Identifiers

PMID42784785
PMCPMC13651898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.