Evidence map›Paper›PMID 42784344›Full record

ReviewTropical medicine and infectious disease2026

Application of Genomics to Prevent and Combat Emerging Infectious Disease Threats in Latin America: Perspectives from an Overseas U.S. Navy Research Command.

Hugo O Valdivia, Maria Silva, Cristopher D Cruz, Paul Rios, Marisa E Lozano, Julia S Ampuero, Yeny Tinoco, Jeffrey Spiro, Yuliya S Johnson, Alden S Estep and 5 more

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hugo O ValdiviaU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0003-2159-5667
Maria SilvaU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.
Cristopher D CruzU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.
Paul RiosU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0002-5690-3378
Marisa E LozanoU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0001-7942-7020
Julia S AmpueroU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0001-5486-1656
Yeny TinocoU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0003-3181-2178
Jeffrey SpiroU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0001-9690-4132
Yuliya S JohnsonU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.
Alden S EstepCenter for Medical, Agricultural and Veterinary Entomology, United States Department of Agriculture's Agricultural Research Service, Gainesville, FL 32608, USA.ORCID 0000-0002-8281-3229
Steev LoyolaU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0001-5455-2423
Carmen Flores-MendozaU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0000-0002-0091-1272
Gissella M VasquezU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.ORCID 0009-0007-0594-8852
Jose A Garcia-RiveraU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.
Henju MarjukiU.S. Naval Medical Research Unit SOUTH, Lima 07006, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endemic and (re)emerging infectious diseases pose a major threat to public health and military readiness in Central and South America. The high biodiversity and the differing transmission pathways require the use of highly sensitive methods to track the emergence and spread of these diseases. High-throughput sequencing technologies have become a critical resource for the field of infectious disease monitoring, specifically for tracking pathogen evolution, antimicrobial resistance, and transmission. This review provides an overview of the implementation of genomics-informed infectious disease surveillance conducted by the U.S. Naval Medical Research Unit SOUTH, focusing on operational, infrastructural, and logistical challenges in resource-limited settings and outlining strategies for building sustainable regional capacity. Selected case studies focused on prominent biothreats including dengue, Oropouche, malaria, and antimicrobial resistance demonstrate the significance and applicability of targeted and agnostic sequencing approaches to elucidate transmission pathways, pathogen discovery, and guide public health responses and field-deployable applications.

Indexed as

emerging infectious diseasesgenomic surveillancehigh-throughput sequencingvector-borne diseases

Identifiers

PMID42784344
PMCPMC13611510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.