ArticleToxins2026
Non-Surgical Ear Rejuvenation Through Selective Neuromodulation with Onabotulinum and Abobotulinum Toxin-A.
Article in Toxins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
To date, there are no studies concerning the ear aging phases, nor adequate anti-aging protocols. The aims of this study are: (1) to propose an aesthetic classification of auricular aging; (2) to evaluate the aesthetic implications, efficacy, and safety levels of botulinum toxin application to the auricles as anti-aging treatment. A retrospective study was conducted in a single center on 40 patients' charts to define an aesthetic ear aging classification, focusing on the muscles involved in the aging process; then an analysis on the results of the treatment of 50 healthy women (50-65 years), with the botulinum toxin type A for ear rejuvenation was conducted; the technique, visual aesthetic results, incidence of side effects, and efficiency of the treatment were presented. All procedures were performed in 2024, and subjects were monitored for the duration of the effects. Auricle aging process may be classified into 4 degrees. The treatment of 50 women with aging ears degree 1-2 permits correction of both ear protrusion and shape. In 1.5% of the auricles, mild swelling and transient bruising at the injection site were observed immediately after the treatment and resolved within 2-3 days. Patient satisfaction was high, and two external reviewers confirmed the treatment's aesthetic efficiency. Aesthetic classification of auricle aging can be a useful tool in anti-aging decision-making. Ear treatment with botulinum toxin type A seems complementary to face treatment. The results are encouraging, but the number of subjects treated is limited. Further studies are required to outline age-related guidelines.
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