ArticleNanomaterials (Basel, Switzerland)2026
Surface-Enhanced Raman Spectroscopy Method for Sensitive Detection of Antibiotic Residues by Layer-Optimized Multilayer Nanoparticle Film Structures.
Article in Nanomaterials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Surface-enhanced Raman scattering (SERS) has been widely applied to food safety screening owing to its high sensitivity and fingerprint recognition. However, SERS faces challenges in practical applications related to the precise control of the number of hot spots and the determination of how many of them actually contribute to the collected signal. In this study, silver nanoparticles (AgNPs) were used to construct a series of layer-tunable AgNP film structures by assembling one to five layers of AgNP thin films using a liquid-liquid interface self-assembly method to obtain a large number of vertically coupled nanogap structures. The relationship between the stacking number and the effective enhancement was evaluated using crystal violet as a probe molecule. The results showed that the SERS intensity increased from one to three layers and then declined, mainly originating from the competition between the vertical plasmon coupling and the finite optical penetration depth; the point-to-point relative standard deviation of the crystal violet signal at 1617 cm
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