Evidence map›Paper›PMID 42783895›Full record

ArticleMarine drugs2026

Bioactive Chitosan Oligosaccharides Derived from Crab Shell Waste Stimulate Osteogenic Differentiation in Pre-Osteoblast Cells.

Supawadee Duangprom, Piyapon Janpan, Sineenart Songkoomkrong, Siriporn Namwongsa, Prateep Amonruttanapun, Jirawat Saetan, Yujun Sung, Vichapol Prasattongosoth, Yutthakan Saengkun, Montakan Tamtin and 2 more

Abstract read
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In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Supawadee DuangpromChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.ORCID 0000-0002-6307-8986
Piyapon JanpanChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.
Sineenart SongkoomkrongChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.
Siriporn NamwongsaChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.ORCID 0009-0007-4785-6251
Prateep AmonruttanapunChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.ORCID 0009-0007-1995-3003
Jirawat SaetanDivision of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
Yujun SungResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathumthani 12120, Thailand.
Vichapol PrasattongosothResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathumthani 12120, Thailand.
Yutthakan SaengkunChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.
Montakan TamtinDepartment of Fisheries, Ministry of Agriculture and Cooperatives, Lat Yao, Chatuchak, Bangkok 10900, Thailand.
Prasert SobhonDepartment of Anatomy, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Napamanee KornthongChulabhorn International College of Medicine, Thammasat University, Rangsit Campus, Pathumthani 12120, Thailand.

Funding

Research Fund of the Chulabhorn International College of Medicine, Thammasat University Grant No. T1/2565Thailand Science Research and Innovation Fundamental FundThammasat Postdoctoral Fellowship Grant No. TUPD6/2569
6 · The paper itself

Abstract

Crustacean shell waste from the seafood industry represents an underutilized food waste with the potential to produce chitosan and chitosan oligosaccharides (COS), with promising applications in bone regeneration. However, the molecular mechanisms of COS during osteogenic differentiation remain uncharacterized. In this study, chitosan was extracted from mud crab (

Indexed as

Animal ShellsBrachyuraCell DifferentiationChitosanOligosaccharidesOsteoblastsOsteogenesisAlkaline PhosphataseAnimalsCell LineCell ProliferationMiceSignal TransductionAlkaline PhosphataseChitosanOligosaccharideschitosanchitosan oligosaccharide (COS)osteogenesistranscriptomics

Identifiers

PMID42783895
PMCPMC13608381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.