ArticleMetabolites2026
Effects of Replacing Fish Meal with Poultry By-Product Meal on Growth, Physiological Status, Disease Resistance, and Hepatic Transcriptomic Responses in Hybrid Yellow Catfish (
Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study evaluated the effects of replacing dietary fish meal (FM) with poultry by-product meal (PBM) on growth, physiological status, disease resistance, and hepatic transcriptomic responses in hybrid yellow catfish (
methodsSix isonitrogenous and isolipidic diets were formulated by replacing 0%, 12%, 24%, 36%, 48%, or 60% of dietary FM with PBM. Juveniles (initial weight 5.18 ± 0.02 g) were fed the experimental diets for 8 weeks.
resultsWeight gain was maximized and the feed conversion ratio minimized in fish fed the FM19 diet, with broken-line regression analysis of weight gain estimating the optimal FM replacement level at 27.4%. Hepatic and intestinal superoxide dismutase activities, as well as intestinal trypsin activity, tended to decline as the level of FM replacement with PBM increased. Following
conclusionsModerate FM replacement with PBM improved growth and feed utilization, whereas excessive replacement was associated with lower antioxidant and digestive enzyme activities, altered metabolic responses, and enhanced expression of inflammation-related genes, supporting PBM as a partial FM substitute in low-FM diets for hybrid yellow catfish.
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