Evidence map›Paper›PMID 42783795›Full record

ArticleMetabolites2026

Search for Novel Biomarkers to Predict Cytochrome P450 2C19 Activity Using Untargeted Metabolomics of Human Plasma.

Ayako Oda, Yosuke Suzuki, Teruhide Koyama, Jun Negami, Sakura Suzuki, Koudai Iino, Nao Yamagishi, Natsuki Kamio, Etsuko Ozaki, Yasuyuki Yamamoto and 10 more

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Ayako OdaDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.ORCID 0009-0005-1423-5622
Yosuke SuzukiDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.
Teruhide KoyamaDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.ORCID 0000-0002-8161-368X
Jun NegamiDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.
Sakura SuzukiDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.
Koudai IinoDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.
Nao YamagishiDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.
Natsuki KamioDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.
Etsuko OzakiDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.ORCID 0000-0002-1225-8303
Yasuyuki YamamotoPublic Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Aichi, Japan.ORCID 0009-0004-6922-4835
Masahiro NakatochiPublic Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Aichi, Japan.ORCID 0000-0002-1838-4837
Yukihide MomozawaLaboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Kanagawa, Japan.
Ryota TanakaDepartment of Clinical Pharmacy, Oita University Hospital, 1-1 Idaigaoka, Hasama-machi, Yufu 879-5593, Oita, Japan.ORCID 0000-0002-8452-7971
Hiroyuki OnoDepartment of Clinical Pharmacy, Oita University Hospital, 1-1 Idaigaoka, Hasama-machi, Yufu 879-5593, Oita, Japan.
Takahiro SumimotoDepartment of Clinical Pharmacy, Oita University Hospital, 1-1 Idaigaoka, Hasama-machi, Yufu 879-5593, Oita, Japan.
Ryosuke TatsutaDepartment of Clinical Pharmacy, Oita University Hospital, 1-1 Idaigaoka, Hasama-machi, Yufu 879-5593, Oita, Japan.ORCID 0000-0003-4949-362X
Hiroki ItohDepartment of Clinical Pharmacy, Oita University Hospital, 1-1 Idaigaoka, Hasama-machi, Yufu 879-5593, Oita, Japan.ORCID 0000-0003-0322-9356
Naoyuki TakashimaDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Keitaro MatsuoDivision of Cancer Epidemiology and Prevention, Aichi Cancer Center, 1-1 Kanokoden, Chigusa-ku, Nagoya 464-8681, Aichi, Japan.ORCID 0000-0003-1761-6314
Keiko OhnoDepartment of Medication Use Analysis and Clinical Research, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose 204-8588, Tokyo, Japan.

Funding

Grants-in-Aid for Scientific Research in Priority Areas of Cancer (No. 17015018) and Innovative Areas (No. 221S0001); No. 17015018;No. 221S0001Japan Society for the Promotion of Science 16H06277Japan Society for the Promotion of Science 22H04923Japan Society for the Promotion of Science 22K06706
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkercytochrome P450 2C19gene polymorphismultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometryuntargeted metabolomics

Identifiers

PMID42783795
PMCPMC13609000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.