Evidence map›Paper›PMID 42783766›Full record

ArticleMetabolites2026

Ruminal Fermentation, Methanogenic Archaeal Diversity, and Metabolomic Responses to

Janaina Silveira da Silva, Rafaela Scalise Xavier de Freitas, Jaqueline Fernandes Bruno, Guilherme Pegoraro Rissi, Eduardo Solano Pina Dos Santos, Vinicius Laerte Silva Herreira, Nara Regina Brandão Cônsolo, Gabriel Henrique Ribeiro, Luiz Alberto Colnago, Ives Cláudio da Silva Bueno

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Janaina Silveira da SilvaDepartment of Animal Science, College of Animal Science and Food Engineering, University of São Paulo (FZEA/USP), Pirassununga 13.635-900, SP, Brazil.ORCID 0000-0002-7808-3729
Rafaela Scalise Xavier de FreitasDepartment of Animal Science, College of Animal Science and Food Engineering, University of São Paulo (FZEA/USP), Pirassununga 13.635-900, SP, Brazil.
Jaqueline Fernandes BrunoDepartment of Animal Science, College of Animal Science and Food Engineering, University of São Paulo (FZEA/USP), Pirassununga 13.635-900, SP, Brazil.ORCID 0000-0001-5180-9211
Guilherme Pegoraro RissiDepartment of Animal Science, College of Animal Science and Food Engineering, University of São Paulo (FZEA/USP), Pirassununga 13.635-900, SP, Brazil.ORCID 0000-0002-1131-4721
Eduardo Solano Pina Dos SantosDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ/USP), Pirassununga 13.635-900, SP, Brazil.ORCID 0000-0002-2928-9405
Vinicius Laerte Silva HerreiraDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ/USP), Pirassununga 13.635-900, SP, Brazil.ORCID 0000-0003-2629-1312
Nara Regina Brandão CônsoloDepartment of Animal Nutrition and Production, School of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ/USP), Pirassununga 13.635-900, SP, Brazil.ORCID 0000-0002-8389-7794
Gabriel Henrique RibeiroBrazilian Agricultural Research Corporation (EMBRAPA) Instrumentation, São Carlos 13.561-206, SP, Brazil.
Luiz Alberto ColnagoBrazilian Agricultural Research Corporation (EMBRAPA) Instrumentation, São Carlos 13.561-206, SP, Brazil.ORCID 0000-0002-9516-9022
Ives Cláudio da Silva BuenoDepartment of Animal Science, College of Animal Science and Food Engineering, University of São Paulo (FZEA/USP), Pirassununga 13.635-900, SP, Brazil.

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo n°2021/14739-4 and 2023/01514-0Fundação de Amparo à Pesquisa do Estado de São Paulo n°2023/14909-2National Council for Scientific and Technological Development 151180/2023-7
6 · The paper itself

Abstract

backgroundPhytogenic feed additives are being explored as alternatives to conventional rumen modulators, yet their effects on the ruminal ecosystem remain insufficiently characterized when assessed only through conventional fermentation parameters. This study evaluated the effects of ethanolic and hydroethanolic extracts of

methodsEight rumen-cannulated wethers were assigned to a replicated 4 × 4 Latin square design with four 28-day periods. Treatments consisted of no additive (CTL), ethanolic extract of

resultsDry matter intake and fermentation parameters were unaffected by treatment. Archaeal alpha diversity showed a contrast-dependent response, with lower Shannon diversity in sheep receiving plant extracts than in those receiving monensin (

conclusions

Indexed as

ethanolic extracthydroethanolic extractovinephytogenic additivesrumen modulatorsuntargeted metabolomics

Identifiers

PMID42783766
PMCPMC13609365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.