Evidence map›Paper›PMID 42783697›Full record

ArticleJournal of functional biomaterials2026

Effects of a Xenogeneic Bone Graft Combined with Platelet-Rich Fibrin Obtained Using Two Distinct Centrifugation Protocols on Critical-Size Rat Calvarial Defects: A Microtomographic, Histomorphometric, and Confocal Laser Scanning Microscopy Analysis.

Ulli da Costa Cunha Martins, Débora de Souza Ferreira Sávio, Roberta Okamoto, Carlos Fernando Mourão, Richard J Miron, Sérgio Luis Scombatti de Souza, Flávia Aparecida Chaves Furlaneto, Michel Reis Messora

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ulli da Costa Cunha MartinsDepartment of Oral and Maxillofacial Surgery and Periodontology (DCTBMF), School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0003-1587-0263
Débora de Souza Ferreira SávioDepartment of Oral and Maxillofacial Surgery and Periodontology (DCTBMF), School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0003-4073-0297
Roberta OkamotoDepartment of Basic Sciences (DCB), School of Dentistry of Araçatuba, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.ORCID 0000-0002-6773-6966
Carlos Fernando MourãoDepartment of Oral and Maxillofacial Surgery and Periodontology (DCTBMF), School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0001-5775-0222
Richard J MironDepartment of Periodontology, School of Dental Medicine, University of Bern, 3010 Bern, Switzerland.
Sérgio Luis Scombatti de SouzaDepartment of Oral and Maxillofacial Surgery and Periodontology (DCTBMF), School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-904, SP, Brazil.
Flávia Aparecida Chaves FurlanetoDepartment of Oral and Maxillofacial Surgery and Periodontology (DCTBMF), School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-8072-3983
Michel Reis MessoraDepartment of Oral and Maxillofacial Surgery and Periodontology (DCTBMF), School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0001-8485-9645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate bone regeneration in critical-size rat calvarial defects treated with a xenogeneic bone graft alone or combined with autologous platelet concentrates prepared using two distinct centrifugation protocols, one based on horizontal centrifugation to produce horizontal platelet-rich fibrin (H-PRF) and the other based on vertical fixed-angle centrifugation to produce leukocyte-platelet-rich fibrin (L-PRF). Calvarial defects were created in 24 rats and allocated to four groups: blood clot (C), xenograft (XEN), xenograft plus L-PRF (XEN+L-PRF), and xenograft plus H-PRF (XEN+H-PRF) (

Indexed as

bone graftbone regenerationhorizontal centrifugationmicro-computed tomographyplatelet-rich fibrin

Identifiers

PMID42783697
PMCPMC13607806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.