Evidence map›Paper›PMID 42783696›Full record

ReviewJournal of functional biomaterials2026

Ultrasound-Responsive Antibacterial Surfaces on Titanium Alloys: A Narrative Review.

Jiayang Gao, Yang Liu, Chenxin Zhan, Meixi Wu, Xinman Wang, Yongheng Zhu, Yuqin Qiao

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiayang GaoInternational Research Center for Food & Health, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China.
Yang LiuMaterdicine Lab, School of Life Sciences, Shanghai University, Shanghai 200444, China.ORCID 0009-0009-8355-1601
Chenxin ZhanMaterdicine Lab, School of Life Sciences, Shanghai University, Shanghai 200444, China.ORCID 0009-0004-6595-585X
Meixi WuMaterdicine Lab, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Xinman WangMaterdicine Lab, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Yongheng ZhuInternational Research Center for Food & Health, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China.
Yuqin QiaoMaterdicine Lab, School of Life Sciences, Shanghai University, Shanghai 200444, China.ORCID 0000-0002-8911-9459

Funding

National Natural Science Foundation of China No. 32171344
6 · The paper itself

Abstract

Ultrasound-responsive antibacterial therapies represent a cutting-edge approach to combating implant-associated infections, particularly advantageous because of ultrasound's non-invasive nature, deep penetration, and ability to target infected areas. However, most previous studies have been devoted to ultrasound-responsive nanomaterials, hydrogels, and polymer systems. Research on ultrasound-responsive surfaces on titanium remains in its early stages and is extremely limited. This review primarily focuses on the design principles and construction strategies for ultrasound-responsive antibacterial surfaces on titanium-based implants, key factors affecting acoustic energy conversion efficiency, and the approaches to enhance antibacterial efficiencies. Based on acoustic energy conversion mechanisms and the primary factors responsible for bacterial killing, this review classifies antibacterial surfaces into sonothermal surfaces, sonodynamic surfaces, and multimodal combined surfaces. Moreover, this review discusses perspectives and challenges regarding biocompatibility, long-term antibacterial activity after implantation, and future clinical translation.

Indexed as

antibacterial surfacesorthopedic implantstitanium alloysultrasound-responsive

Identifiers

PMID42783696
PMCPMC13608181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.