Evidence map›Paper›PMID 42783550›Full record

ArticleJournal of developmental biology2026

PBX3 Promotes Oligodendrocyte Progenitor Cell Proliferation and Differentiation During Early Postnatal Development.

Yanling Yang, Jing Ling, Zhongzhe Zhang, Jie Yuan, Kaixiang Zhang, Xiang Xiao, Hui Guo, Ming Zhang, Xianghui Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanling YangYan'an Medical College, Yan'an University, Yan'an 716000, China.
Jing LingYan'an Medical College, Yan'an University, Yan'an 716000, China.
Zhongzhe ZhangDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Jie YuanDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Kaixiang ZhangDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Xiang XiaoDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Hui GuoSchool of Life Sciences, Central South University, Changsha 410083, China.
Ming ZhangDepartment of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0001-9181-5739
Xianghui ZhaoYan'an Medical College, Yan'an University, Yan'an 716000, China.ORCID 0000-0003-1165-0140

Funding

China Postdoctoral Science Foundation BX20230484National Natural Science Foundation of China 32371021Shanxi Province Youth Development Foundation 2024JC-JCQN-75STI 2030-Major Project 2021ZD0201704
6 · The paper itself

Abstract

Pre-B-cell leukemia transcription factor 3 (PBX3) is a TALE homeodomain protein involved in neural development, but its function in oligodendrocyte (OL) differentiation has remained unexplored. Here, we show that PBX3 expression is dynamically regulated during OL lineage progression, with peak expression in the corpus callosum at P14, corresponding to the onset of active myelination. In cultured primary oligodendrocyte precursor cells (OPCs), PBX3 expression peaked at OL-1DIV, an early stage of in vitro differentiation. Using OL lineage-specific

Indexed as

developmentmyelinationoligodendrocytePBX3

Identifiers

PMID42783550
PMCPMC13608693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.