SynthesisMedical sciences (Basel, Switzerland)2026
Switching from Vitamin K Antagonists to Direct Oral Anticoagulants in Frail Elderly Patients with Atrial Fibrillation: Systematic Review and Meta-Analysis.
Paschalis Karakasis, Ricardo Gómez-Huelgas, Stylianos Tzeis, Konstantinos Vlachos, Konstantinos C Siontis, Alberto M Marra, Konstantinos Pamporis, Antonios P Antoniadis, Eleftheria Lefkou, Valentin A Kokorin and 2 more
Abstract readMeta-AnalysisSystematic Review
In one paragraphSynthesis in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Paschalis KarakasisSecond Department of Cardiology, Aristotle University of Thessaloniki, Hippokration General Hospital, 546 42 Thessaloniki, Greece.ORCID 0000-0002-3561-5713 Ricardo Gómez-HuelgasInternal Medicine Department, Regional University Hospital of Málaga, Biomedical Research Institute of Málaga (IBIMA), University of Málaga (UMA), 29010 Malaga, Spain.ORCID 0000-0002-9909-3555 Stylianos TzeisDepartment of Cardiology, Mitera Hospital, 6 Erythrou Stavrou Str., 151 23 Marousi, Greece.
Konstantinos VlachosElectrophysiology and Heart Modeling Institute, IHU Liryc, Fondation Bordeaux Université, Université de Bordeaux, INSERM U1045, 33604 Pessac, France.ORCID 0000-0002-7543-3236 Konstantinos C SiontisDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Alberto M MarraDepartment of Translational Medical Sciences, "Federico II" University, 80131 Naples, Italy.ORCID 0000-0002-9679-3003 Konstantinos PamporisFirst Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, 115 27 Athens, Greece.ORCID 0000-0001-5411-6461 Antonios P AntoniadisSecond Department of Cardiology, Aristotle University of Thessaloniki, Hippokration General Hospital, 546 42 Thessaloniki, Greece.ORCID 0000-0002-6604-5581 Eleftheria LefkouHematology-Transfusion Medicine Department, Faculty of Medicine, Larissa University Hospital, University of Thessaly, 413 34 Larissa, Greece.
Valentin A KokorinDepartment of Hospital Therapy with Courses in Endocrinology, Hematology and Clinical Laboratory Diagnostics, Peoples' Friendship University of Russia Named after Patrice Lumumba (RUDN University), Moscow 117198, Russia.
Dimitrios PatouliasSecond Propedeutic Department of Internal Medicine, Faculty of Medicine, School of Health Sciences Aristotle, University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0002-6899-684X Nikolaos FragakisSecond Department of Cardiology, Aristotle University of Thessaloniki, Hippokration General Hospital, 546 42 Thessaloniki, Greece.ORCID 0000-0002-7158-4950 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
AnticoagulantsAtrial FibrillationDrug SubstitutionVitamin KAdministration, OralAgedAged, 80 and overFrail ElderlyHemorrhageHumansStrokeAnticoagulantsVitamin Kanticoagulationatrial fibrillationdirect oral anticoagulantselderlyfrailtymajor bleedingmortalityswitchingthromboembolismvitamin K antagonistswarfarin
Identifiers
PMID42783389
PMCPMC13609571
What OpenQuestion holds
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