Evidence map›Paper›PMID 42783307›Full record

ReviewInsects2026

Renaming the 'OS-D/CSP' Family (Part 2): '4-Cysteine Soluble Proteins' (4CSPs)-Intracellular Functions.

Guoxia Liu, Botong Sun, Wei Fan, Shousong Yue, Qiuxia He, Jean-François Picimbon

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Insects, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guoxia LiuShandong Academy of Agricultural Sciences, Jinan 250100, China.
Botong SunScience and Technology Service Platform of Shandong Academy of Sciences, Shandong Academy of Sciences Foreign Students Pioneer Park, Shandong Academy of Sciences, Jinan 250103, China.
Wei FanScience and Technology Service Platform of Shandong Academy of Sciences, Shandong Academy of Sciences Foreign Students Pioneer Park, Shandong Academy of Sciences, Jinan 250103, China.
Shousong YueShandong Academy of Agricultural Sciences, Jinan 250100, China.
Qiuxia HeScience and Technology Service Platform of Shandong Academy of Sciences, Shandong Academy of Sciences Foreign Students Pioneer Park, Shandong Academy of Sciences, Jinan 250103, China.
Jean-François PicimbonShandong Academy of Agricultural Sciences, Jinan 250100, China.ORCID 0000-0002-9440-4772

Funding

Ministry of Science and Technology of China-National Expert title G2022023033LOverseas High-Level Talent Program-Taishan Scholar title NO. tshw20091015
6 · The paper itself

Abstract

The gut, brain, fat body, and various glands, although rich in "CSPs", are not involved in chemosensory functions. We propose renaming the "CSPs" to "4CSPs" (4-Cysteine Soluble Proteins) to clarify their role, avoiding confusion with proteins also found in wings, hemolymph, and eggs. This report highlights studies related to insecticide resistance and lipid transport and expands on potential intracellular functions, strongly indicating non-chemosensory features of 4CSPs. Additionally, we show a significant correlation between 4CSPs and mucins, translation initiation factors, and actin complex proteins, reinforcing the proposal to rename "CSPs" and consider developmental pattern, tissue distribution, and intracellular localization.

Indexed as

4CSP (4-Cysteine Soluble Protein)actin skeleton regulatory complexcell regulationmucinN-4CSPnuclear pore complex proteintranscription initiation factor

Identifiers

PMID42783307
PMCPMC13607926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.