ArticleBiosensors2026
A Robust Electrochemical Aptasensor Based on a AuNP/Chitosan Conductive Network for Saxitoxin Detection in Freshwater Samples.
Article in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Saxitoxin (STX) is a highly potent marine biotoxin, and trace contamination in aquatic environments can pose serious risks to human health. Therefore, reliable detection of low-concentration STX is crucial for water safety monitoring. Here, we developed a robust electrochemical aptasensor based on a gold nanoparticle/chitosan (AuNP/CS) conductive network for STX detection in freshwater samples. The chitosan matrix provides a three-dimensional scaffold for aptamer immobilization, while interconnected AuNPs create efficient electron-transfer pathways across the sensing interface. This integrated architecture improves interfacial conductivity and supports stable target-induced aptamer recognition. The aptasensor exhibits a linear response from 1 to 1000 nM and a limit of detection of 0.74 nM, with an apparent dissociation constant K
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