Evidence map›Paper›PMID 42783071›Full record

ArticleJournal of cardiovascular development and disease2026

Association Between Prognostic Nutritional Index and Clinical Outcomes After Percutaneous Coronary Intervention in Elderly Patients with Chronic Total Occlusion.

Jiquan Xiao, Song Wen, Renshang Xu, Qiheng Wan, Xiang He, Yusi Huang, Wenzhi Hu, Bin Zhang, Huimin Yu

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In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jiquan XiaoDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Song WenDepartment of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.ORCID 0000-0002-1648-5722
Renshang XuDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Qiheng WanDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.ORCID 0009-0005-8544-0367
Xiang HeDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Yusi HuangDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Wenzhi HuDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Bin ZhangDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.
Huimin YuDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.

Funding

Guangzhou Municipal Science and Technology Bureau grant no. 2024B03J1340National Center for Chronic and Noncommunicable Disease Control and Prevention grant no. 2024ZD0526803
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the association between the prognostic nutritional index (PNI) and long-term all-cause mortality and major adverse cardiovascular events (MACEs) in elderly patients with chronic total occlusion (CTO) after successful percutaneous coronary intervention (PCI).

methodsThis retrospective study enrolled 745 consecutive patients aged ≥ 60 years with successfully revascularized CTO between February 2011 and April 2023. All-cause mortality was the primary endpoint. MACE, defined as the first occurrence of all-cause mortality, non-fatal myocardial infarction, stroke, or target-vessel revascularization (TVR), was the secondary endpoint. Cox proportional hazards models and restricted cubic spline (RCS) analyses were used to evaluate associations.

resultsDuring a median follow-up of 813 days, 58 (7.8%) all-cause mortality and 101 (13.6%) MACE occurred. In the primary multivariable model (Model 2), each 1-unit increase in PNI was associated with a 15% reduced risk of all-cause mortality (HR 0.85, 95% CI 0.81-0.90;

conclusionIn this single-center retrospective cohort of elderly patients after successful CTO-PCI, lower baseline PNI was associated with higher risks of all-cause mortality and MACE. PNI may be a useful risk stratification tool, but its clinical utility requires confirmation in prospective, externally validated studies before implementation.

Indexed as

all-cause mortalitychronic total occlusionmajor adverse cardiovascular eventspercutaneous coronary interventionprognostic nutritional index

Identifiers

PMID42783071
PMCPMC13607444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.