Evidence map›Paper›PMID 42782887›Full record

ArticleCurrent oncology (Toronto, Ont.)2026

Investigating Quality of Life and Decision Regret in Patients Undergoing Laryngectomy.

Dagmawi Lulseged, Jedeiah Dickerson, Lauren Ottenstein, Margie Dixon, Rebecca Pentz, Nicole C Schmitt

Abstract readComparative Study
In one paragraph

Article in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dagmawi LulsegedWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Jedeiah DickersonWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0009-0000-3488-1510
Lauren OttensteinWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0003-4071-1512
Margie DixonWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.
Rebecca PentzWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0003-4338-6663
Nicole C SchmittWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0002-0571-3531

Funding

Patient Oriented Research in Communication and Swallowing DisordersK24DC022077 · NIDCD · EMORY UNIVERSITY · PI Nicole Cherie Schmitt · 2024 to 2026
$433k
NIDCD NIH HHS K24 DC022077NIH HHS 1K24DC022077-26
6 · The paper itself

Abstract

Total laryngectomy is a surgical procedure for advanced laryngeal cancer and can affect speech, swallowing, and breathing. This study compared the quality of life, swallowing function, and decision regret among patients who underwent primary total laryngectomy with adjuvant radiation (Group 1) versus salvage laryngectomy (Group 2). A survey was completed by 25 Group 1 patients and 27 Group 2 patients. Quality of life and swallowing ability were assessed using the University of Washington Quality of Life Questionnaire (UW-QOL) and M.D. Anderson Dysphagia Inventory (MDADI), while decision regret was measured using the Decision Regret Scale. Group 1 patients reported a higher mean total UW-QOL score (74.4) than Group 2 (68.2). Similarly, Group 1 patients demonstrated better swallowing outcomes, with a mean MDADI score of 70.28 compared to 63.90 in Group 2. Decision Regret scores were lower in Group 1 patients (31.4) than in Group 2 (35.37), indicating less regret regarding treatment decisions. However, all these differences did not reach statistical significance. Overall, these findings highlight the importance of fully informing patients of the impact of surgery on quality of life to assist them in their decision-making. Future studies can recruit larger cohorts and investigate the effectiveness of other laryngectomy treatments/procedures.

Indexed as

Decision MakingEmotionsLaryngeal NeoplasmsLaryngectomyAdultAgedAged, 80 and overCohort StudiesDeglutition DisordersFemaleHumansMaleMiddle AgedPostoperative ComplicationsQuality of LifeRadiotherapy, Adjuvantdecision regretquality of lifesalvage laryngectomyswallowingtotal laryngectomy with radiation

Identifiers

PMID42782887
PMCPMC13605748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.