ArticleCurrent oncology (Toronto, Ont.)2026
Reclassification of
Yueran Shen, Jiuan Chen, Li Hu, Jie Sun, Juan Zhang, Lu Yao, Ye Xu, Yuntao Xie
Abstract read
In one paragraphArticle in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Yueran ShenFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.
Jiuan ChenFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.
Li HuFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.
Jie SunFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.ORCID 0000-0002-3466-1371 Juan ZhangFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.
Lu YaoFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.ORCID 0000-0002-6430-8712 Ye XuFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.ORCID 0000-0002-5520-3839 Yuntao XieFamilial & Hereditary Cancer Center, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing 100142, China.ORCID 0000-0003-1151-8107 Funding
National Natural Science Foundation of China 82072898National Natural Science Foundation of China 92359201
6 · The paper itselfAbstract
purposeTo evaluate the pathogenicity of
methodsA total of 15,092 breast cancer patients were enrolled in this study, among which 457 distinct
resultsOf these 88 evaluated
conclusionSGE-based functional scoring system provides a reliable approach for reclassifying
Indexed as
BRCA2 ProteinBreast NeoplasmsGene EditingAdultAgedFemaleGenetic Predisposition to DiseaseHumansMiddle AgedPhenotypeBRCA2 ProteinBRCA2 protein, humanBRCA2breast cancerclinical phenotypesaturation genome editingvariants of uncertain significance
Identifiers
PMID42782867
PMCPMC13605375
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