ArticleCells2026
Targeting NCAM1/FGFR1 Signaling to Alleviate Sleep Disturbance-Induced Neuroinflammation in the Hypothalamus.
Yanxiang Qu, Bo Li, Shixuan Yan, Chuanjie Zhang, Guohua Ji, Kai Li, Yujie Zhao, Zuoyang Wang, Xiaopeng Li, Bo Song and 1 more
Abstract read
In one paragraphArticle in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Yanxiang QuDepartment of Pathology and Forensics, Dalian Medical University, Dalian 116044, China.
Bo LiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Shixuan YanState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Chuanjie ZhangState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Guohua JiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Kai LiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.ORCID 0000-0002-8348-317X Yujie ZhaoState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Zuoyang WangState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.
Xiaopeng LiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.ORCID 0009-0008-2687-1695 Bo SongDepartment of Pathology and Forensics, Dalian Medical University, Dalian 116044, China.
Lina QuState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing 100094, China.ORCID 0000-0002-6374-415X Funding
Foundation of State Key Laboratory of Space Medicine, China Astronaut Research and Training Center SKL2024Y07; SKL2024J01; SKL2024Z01National Key R&D Program of China (2022YFA1604503) 2022YFA1604503
6 · The paper itselfAbstract
Sleep disturbance is a prevalent public health concern associated with cognitive deficits and emotional dysregulation, yet the mechanisms underlying SD-induced hypothalamic dysfunction remain incompletely understood. Here, we found that two weeks of SD induced marked hypothalamic neuroinflammation, accompanied by increased expression of the pro-inflammatory cytokines
Indexed as
HypothalamusNeural Cell Adhesion MoleculesNeuroinflammatory DiseasesReceptor, Fibroblast Growth Factor, Type 1Signal TransductionSleep Wake DisordersAnimalsCytokinesInflammationLipopolysaccharidesMaleMiceMice, Inbred C57BLMicrogliaNeuronsCytokinesFgfr1 protein, mouseLipopolysaccharidesNeural Cell Adhesion MoleculesReceptor, Fibroblast Growth Factor, Type 1activation of microgliahypothalamusinhibitory neuronsNCAM1/FGFR1 interactionneuroinflammationsleep disturbance
Identifiers
PMID42782816
PMCPMC13605233
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