ArticleCells2026
A Novel SINE Transposable Element-Associated lncRNA Regulates Zygotic Genome Activation in Porcine Parthenogenetically Activated Embryos.
Tianyao He, Shanlong Zhang, Shichao Zhang, Dongsong Liu, Han Li, Jun Song, Zhonghua Liu, Jun-Xue Jin, Jing-Tao Sun
Abstract read
In one paragraphArticle in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
Tianyao HeKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID 0009-0003-5300-7329 Shanlong ZhangKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
Shichao ZhangKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
Dongsong LiuKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
Han LiKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
Jun SongKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-6128-6378 Zhonghua LiuKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-9199-6493 Jun-Xue JinKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
Jing-Tao SunKey Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
Funding
China Postdoctoral Science Foundation 2025T180067National Natural Science Foundation of China 32372884National Natural Science Foundation of China 32402761Natural Science Foundation of Heilongjiang Province of China ZL2024C013Postdoctoral Fellowship Program of CPSF GZB20240132
6 · The paper itselfAbstract
Zygotic genome activation (ZGA) is a pivotal event during early mammalian embryonic development and is regulated by multiple molecular factors. In mice, previous studies have demonstrated that long non-coding RNAs (lncRNAs) and transposable elements (TEs) participate in the regulation of this process. However, the functional roles of TEs-associated lncRNAs in porcine ZGA remain largely unknown. In this study, we identified a previously unannotated lncRNA associated with a SINE transposable element sequence in porcine parthenogenetically activated embryos, which we named
Indexed as
DNA Transposable ElementsEmbryo, MammalianGenomeParthenogenesisRNA, Long NoncodingShort Interspersed Nucleotide ElementsZygoteAnimalsE1A-Associated p300 ProteinEmbryonic DevelopmentFemaleGene Expression Regulation, DevelopmentalSwineDNA Transposable ElementsE1A-Associated p300 ProteinRNA, Long Noncodingembryo developmentEP300lncRNASINE-associated lncRNAZGA
Identifiers
PMID42782807
PMCPMC13605572
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