Evidence map›Paper›PMID 42782769›Full record

ReviewCells2026

Coupling Dysfunction of Mitochondria and Actin in Loss of Native Gastric Glands: A Mechanistic Hypothesis for Chronic Atrophic Gastritis Pathogenesis.

Wenxin Wei, Yue Ma, Shujie Wang, Cisong Cheng

Abstract readReview
In one paragraph

Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenxin WeiSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0009-0000-9750-8932
Yue MaSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0009-0009-5255-333X
Shujie WangSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Cisong ChengSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progressive loss of native gastric glands in chronic atrophic gastritis (CAG) represents a critical step toward gastric carcinogenesis, yet the underlying cellular structural mechanisms remain incompletely understood. In this review, we formulate an integrative mechanistic hypothesis that disruption of actin cytoskeletal homeostasis, driven by mitochondrial bioenergetic dysfunction, plays a central role in the progressive loss of native gastric glands. Persistent

Indexed as

ActinsGastric MucosaGastritis, AtrophicMitochondriaAnimalsHumansActinsactin cytoskeletonchronic atrophic gastritisglandular atrophyinflammation-driven carcinogenesismitochondrial damage

Identifiers

PMID42782769
PMCPMC13605486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.