Evidence map›Paper›PMID 42782678›Full record

ArticleBiomimetics (Basel, Switzerland)2026

Full-Thickness Regeneration of the Hard Palate Using Bioengineered Mucoperiosteal Scaffolds in a Porcine Model.

Maria Ida Rizzo, Maria Emiliana Caristo, Chiara Ribaldone, Simone Faustino Maria Marino, Giorgio Spuntarelli, Anna Chiara Contini, Luigi Dall'Oglio, Luigi Tomao, Mattia Algeri, Stefano Tedesco and 8 more

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In one paragraph

Article in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maria Ida RizzoDepartment of Plastic and Maxillofacial Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-3856-5010
Maria Emiliana CaristoCentro Ricerche Sperimentali, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Chiara RibaldoneDepartment of Plastic and Maxillofacial Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Simone Faustino Maria MarinoDepartment of Plastic and Maxillofacial Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Giorgio SpuntarelliDepartment of Plastic and Maxillofacial Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Anna Chiara ContiniGastroenterology and Nutrition Unit, Digestive Endoscopy and Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Luigi Dall'OglioGastroenterology and Nutrition Unit, Digestive Endoscopy and Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Luigi TomaoDepartment of Pediatric OncoHematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-4774-3042
Mattia AlgeriDepartment of Pediatric OncoHematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-6673-2664
Stefano TedescoTelea Biotech and Telea Electronic Engineering, 36066 Sandrigo, Italy.ORCID 0000-0001-8492-5948
Gianantonio PozzatoTelea Biotech and Telea Electronic Engineering, 36066 Sandrigo, Italy.
Cristiano De StefanisResearch Laboratories, Histology Core Facility, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-5898-9518
Antonello CardoniDepartment of Anatomical Pathology, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Lorenzo LupoiCentro Ricerche Sperimentali, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Camilla CodazziDepartment of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0009-5646-3980
Lucia LeoneDepartment of Neuroscience, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-5567-7375
Mario ZamaDepartment of Plastic and Maxillofacial Surgery, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Massimiliano RaponiManagement and Diagnostic Innovations & Clinical Pathways Research Area, Medical Directorate, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

Funding

Italian ministry of health
6 · The paper itself

Abstract

Cleft palate is a congenital anomaly that causes functional and esthetic challenges, and the hard palate is essential for feeding, speech, and separation of the oral and nasal cavities. Yet, current reconstructive techniques do not restore its bony component. Building on previous in vitro work showing that decellularized palatal mucoperiosteum, microperforated with Quantum Molecular Resonance (QMR

Indexed as

bioengineered scaffoldbone regenerationcleft palatedecellularized mucoperiosteummesenchymal stem cellstissue engineering

Identifiers

PMID42782678
PMCPMC13604190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.