Evidence map›Paper›PMID 42782525›Full record

ReviewInternational urogynecology journal2026

Vaginal Natural Orifice Endoscopic Surgery for Primary Uterovaginal Prolapse: Evidence, Evolution, and Standardized Surgical Technique for Uterosacral Ligament Suspension.

Yasnaia Bruneel, Anna Zdroik, Catherine A Matthews, Jan Baekelandt

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In one paragraph

Review in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yasnaia BruneelDepartment of Gynecology, Imelda Hospital, Bonheiden, Belgium.
Anna ZdroikDepartment of Obstetrics and Gynecoloogy, TriHealth, Cincinnati, OH, USA.
Catherine A MatthewsDepartment of Urology, Wake Forest University School of Medicine, Winston Salem, NC, USA.
Jan BaekelandtDepartment of Development and Regeneration, University of Leuven, Leuven, Belgium. Jan.Baekelandt@imelda.be.ORCID http://orcid.org/0000-0002-8344-8622

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisVaginal natural orifice transluminal endoscopic surgery (vNOTES) has emerged as a minimally invasive approach for primary uterovaginal prolapse with increasing application in urogynecology. A systematic review published in 2025 supports vNOTES uterosacral ligament suspension (USLS) as an alternative mode of access with favorable perioperative anatomic and patient-centered outcomes compared to conventional transvaginal repair.

methodsIn April 2026, a consensus conference on controversies in the surgical management of primary uterovaginal prolapse (U-POP) was conducted with the overarching goal of developing an evidence-based algorithm for surgical decision-making and standardizing best-practice surgical techniques for U-POP. For vNOTES USLS, a 2025 systematic review served as the primary evidence base for generation of consensus statements that were submitted for delphi voting. A recommendation for preferred surgical technique of vNOTES USLS was developed on the basis of expert opinion.

resultsCurrent evidence suggests improved operative efficiency, low complication rates, and improved visualization of the ureters and pelvic sidewall anatomy compared to conventional vaginal uterosacral ligament suspension. This review describes the integration of vNOTES in urogynecology, reviews the current evidence regarding safety and outcomes, and provides stepwise surgical technique and best-practice considerations for vNOTES USLS for the surgical treatment of primary U-POP with accompanying videos.

conclusionsvNOTES provides improved visualization of the uterosacral ligaments and using a standardized technique, may offer advantages over laparoscopic and conventional transvaginal uterosacral ligament suspension for primary uterovaginal prolapse repair.

Indexed as

Minimally invasive surgeryPelvic organ prolapseUterosacral ligament suspensionVaginal natural orifice transluminal endoscopic surgeryVNOTES

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.