Evidence map›Paper›PMID 42782397›Full record

ReviewClinical oral investigations2026

The DC/TMD Conundrum.

Daniele Manfredini, Gary D Klasser, Alessandro Bracci, Charles S Greene, Louis G Mercuri, Sanjvan Kandasamy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniele ManfrediniSchool of Dentistry, Department of Medical Biotecnhologies, University of Siena, c/o Policlinico Universitario Le Scotte Viale Bracci, Siena, 53100, Italy. daniele.manfredini@unisi.it.
Gary D KlasserDepartment of Diagnostic Sciences, Louisiana State University School of Dentistry, New Orleans, USA.
Alessandro BracciSchool of Dentistry, Department of Neurosciences, University of Padova, Padova, Italy.
Charles S GreeneDepartment of Orthodontics, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA.
Louis G MercuriDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Sanjvan KandasamyDental School, The University of Western Australia, Nedlands, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe goal of any disease classification system, based on the core principles of translational and evidence-based medicine, is to develop management plans that provide appropriate high-quality patient care based on accurate diagnoses, according to the core principles of translational medicine. MATERIALS AND

methodsWithin these premises, the current classification schemes that are available in the field of temporomandibular disorders (TMDs) practice are hardly clinically useful and patient oriented. The publication of the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) is a milestone achievement that serves as a foundation of the discipline, but it clearly lacks the needed impact on the everyday practice and treatment planning. From being the potential solution to the necessity of standardizing TMD classification, the DC/TMD became an enigma in search of a solution: how to progress and move on to embed current evidence-based knowledge into a diagnostic and classification schemes that can be adopted both for academic and clinical purposes?

resultsThis manuscript provides an overview of the reasons why the time has come to rethink, reconceptualize and reconfigure the currently accepted concepts and develop concepts based on the current body of evidence that provide improved clinical usefulness and medical semantics.

conclusionsThere will be a long and difficult task ahead, but it is time to get to work and try solving the DC/TMD conundrum for the advancement of our field and enhanced care for our patients. CLINICAL RELEVANCE: The field of orofacial pain and temporomandibular disorders is constantly evolving, and the need for patient-oriented, clinical-friendly classification systems that facilitate treatment plan is emerging.

Indexed as

Temporomandibular Joint DisordersEvidence-Based MedicineFacial PainHumansClassificationDC/TMDDiagnosisOrofacial PainTemporomandibular Disorders

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.