ArticleEuropean journal of applied physiology2026
Effects of different sodium bicarbonate supplementation strategies on repeated 3-min all-out cycling performance and blood acid-base responses.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study compared four sodium bicarbonate (SB) supplementation strategies differing in dose and dosing pattern on end-test power (EP), work performed above EP (WEP), and blood acid-base responses during two 3-min all-out cycling tests (3MTs) separated by 70 min.
methodsSixteen trained men completed a randomized crossover study involving four SB conditions: single-dose moderate-SB (SM-SB), multiple-dose moderate-SB (MM-SB), single-dose higher-SB (SH-SB), and multiple-dose higher-SB (MH-SB), and placebo (PLA). The SB conditions comprised 0.3-0.4 g·kg⁻¹ body mass administered as a single or multiple dose. Ninety minutes after supplementation, participants performed two 3MTs separated by 70 min, with blood variables measured before and after each bout and during recovery.
resultsOverall WEP showed significant main effects of supplementation condition (F = 4.10, ηp² = 0.11, P < 0.05) and time (F = 13.50, ηp² = 0.09, P < 0.05), with no significant condition × time interaction. During 3MT1, WEP was higher with SM-SB and MH-SB than PLA (~ 17.9% and ~ 18.6%, respectively; P < 0.05), with a significant condition main effect. Whereas during 3MT2, WEP was higher with SH-SB than PLA (~ 15.7%, P < 0.05), despite no significant condition main effect. EP showed no supplementation condition × time interaction (F = 0.60, ηp² = 0.02, P > 0.05) or supplementation condition main effect, but differed between 3MT1 and 3MT2 (F = 11.07, ηp² = 0.08, P < 0.05). A significant supplementation condition × time interaction was observed for blood [HCO
conclusionSB supplementation increased overall WEP across repeated 3MTs, although the ergogenic effects were more evident during the first bout. Divided ingestion of 0.4 g·kg
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