Evidence map›Paper›PMID 42782024›Full record

ArticleJACC. Case reports2026

Successful Heart Transplantation in a Patient With Triple Infiltrative Cardiomyopathy: Sarcoidosis, AL and TTR Amyloidosis.

Lazaros A Nikolaidis, Ossama A Hassan, Yevgeniy Khariton, Ebere Chukwu, Ernesto Ruiz, Jaime Hernandez-Montfort, Debby Rampisela, Madison Bahe, Amber Malhotra, Pankaj Garg

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In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lazaros A NikolaidisDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA. Electronic address: Lazaros.Nikolaidis@BSWHealth.org.
Ossama A HassanDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Yevgeniy KharitonDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Ebere ChukwuDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Ernesto RuizDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Jaime Hernandez-MontfortDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Debby RampiselaDepartment of Pathology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Madison BaheDepartment of Cardiology, Baylor Scott and White Medical Center, Temple, Texas, USA.
Amber MalhotraDepartment of Cardiothoracic Surgery, Baylor Scott and White Medical Center, Temple, Texas, USA.
Pankaj GargDepartment of Cardiothoracic Surgery, Baylor Scott and White Medical Center, Temple, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough "dual pathology" cardiac amyloidosis cases (amyloid light chain [AL] and transthyretin [TTR]) have been described, the coexistence of cardiac sarcoidosis with TTR amyloidosis is extremely rare, with only 2 case reports described in Japan to date. REPORT SUMMARY: We describe a unique case of a triple pathology consisting of cardiac sarcoidosis and both AL and TTR amyloidosis identified in myocardial tissue by liquid chromatography tandem mass spectrometry as well as advanced cardiac magnetic resonance and fluorodeoxyglucose positron emission tomography scans in the same patient. DISCUSSION-NOVELTY: To the best of our knowledge, this is not only the first patient with a triple infiltrative cardiac pathology but also the first such patient who underwent successful heart transplantation, with the above pathologies confirmed by the explanted native heart. TAKE-HOME MESSAGE: Coexistence of cardiac sarcoidosis, TTR and AL amyloidosis in the same patient's native heart poses unique therapeutic challenges regarding post-transplantation medical management.

Indexed as

cardiac transplantcardiomyopathychronic heart failure

Identifiers

PMID42782024
PMCPMC13616549

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