Evidence map›Paper›PMID 42782015›Full record

ArticleJACC. Advances2026

Bayesian Network Meta-Analysis of Long-Term Survival: Single vs Multiple vs Total Arterial Coronary Bypass Grafting.

Justin Ren, Christopher M Reid, David H Tian, Christopher Siderakis, Julian A Smith, Colin Royse, Andrea Bowyer, Ximena Cid-Serra, Winnie Zhang, Gina Arena and 1 more

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Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Justin RenDepartment of Surgery, The University of Melbourne, Melbourne, Australia; Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, Australia; Medical School, The University of Western Australia, Perth, Australia.
Christopher M ReidPopulation Health, Curtin University, Perth, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
David H TianDepartment of Surgery, The University of Melbourne, Melbourne, Australia; Department of Anesthesia and Perioperative Medicine, Westmead Hospital, Sydney, Australia.
Christopher SiderakisDepartment of Surgery, The University of Melbourne, Melbourne, Australia.
Julian A SmithDepartment of Surgery, Monash University, Melbourne, Australia; Department of Cardiothoracic Surgery, Monash Health, Melbourne, Australia.
Colin RoyseDepartment of Surgery, The University of Melbourne, Melbourne, Australia; Department of Anesthesia and Pain Management, The Royal Melbourne Hospital, Melbourne, Australia; Outcomes Research, University of Texas Health, Houston, Texas, USA.
Andrea BowyerDepartment of Surgery, The University of Melbourne, Melbourne, Australia; Department of Anesthesia and Pain Management, The Royal Melbourne Hospital, Melbourne, Australia.
Ximena Cid-SerraDepartment of Surgery, The University of Melbourne, Melbourne, Australia.
Winnie ZhangMedical School, The University of Western Australia, Perth, Australia.
Gina ArenaMedical School, The University of Western Australia, Perth, Australia.
Alistair RoyseDepartment of Surgery, The University of Melbourne, Melbourne, Australia; Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, Australia. Electronic address: Alistair.Royse@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArterial conduit strategies in coronary artery bypass grafting (CABG) have been associated with superior graft durability to saphenous vein grafts. However, the relative benefits of multiple arterial grafting (MAG) and total arterial revascularization (TAR) remain uncertain due to limited direct comparative evidence.

objectivesThis systematic review and Bayesian network meta-analysis (PROSPERO; CRD420251117898) evaluated long-term survival outcomes associated with single arterial grafting (SAG), MAG, and TAR.

methodsMedical Literature Analysis and Retrieval System Online, Excerpta Medica Database, and the Cochrane Library were searched from inception to March 2026 for studies comparing CABG conduit strategies reporting adjusted HRs for long-term all-cause mortality. Studies including adults undergoing isolated CABG with SAG, MAG, or TAR were eligible. A Bayesian random-effects network meta-analysis was performed to integrate direct and indirect evidence. This framework permitted quantification of TAR-versus MAG comparisons, which had previously been limited by scarce direct evidence. Treatment ranking was assessed using the surface under the cumulative ranking curve.

resultsFifty-four studies including 560,723 patients were analyzed. Compared with SAG, MAG was associated with lower long-term mortality (HR: 0.83; 95% credible interval [CrI]: 0.79-0.85), whereas TAR demonstrated a greater survival benefit (HR: 0.75; 95% CrI: 0.70-0.79). Indirect comparison within the network suggested an incremental survival advantage of TAR over MAG (HR: 0.90; 95% CrI: 0.85-0.96). Treatment ranking suggested a hierarchy in which TAR was associated with superior survival, followed by MAG and SAG.

conclusionsIncreasing use of arterial conduits during CABG is associated with progressively improved long-term survival, with TAR demonstrating the greatest benefit.

Indexed as

Bayesian network meta-analysiscoronary artery bypass graftingmultiple arterial graftingsurvival analysistotal arterial revascularization

Identifiers

PMID42782015
PMCPMC13616513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.