ArticlePsoriasis (Auckland, N.Z.)2026
Ultrasound Renal Stress Test Assessment in Moderate-to-Severe Psoriasis: A Pilot Study.
Article in Psoriasis (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Psoriasis is increasingly recognized as a systemic inflammatory disease and has been associated with chronic kidney disease. Whether psoriasis is also linked to subclinical impairment in renal microcirculation remains unclear. Objective: To assess renal functional reserve (RFR) in patients with moderate-to-severe psoriasis using the renal stress test (RST). Methods: Fifty-one consecutive adults with psoriasis and 35 age- and sex-matched controls underwent RST. Renal resistive index (RRI) was measured by Doppler ultrasound in an interlobular renal artery at baseline and after abdominal compression with a fluid-filled bag corresponding to 10% of body weight. Intrarenal resistive index variation (IRRIV) was calculated as the percentage difference between baseline and stress values. Results: Patients with psoriasis showed a lower IRRIV than controls (median 13.8% [10.7-18.6] vs 23.1% [17.8-25.0]; p<0.001). IRRIV differed significantly across controls and Psoriasis Area and Severity Index (PASI) severity strata (p<0.001), but post hoc pairwise comparisons showed that this difference was driven by the comparison between controls and psoriasis patients, with no significant difference between severity strata. In multivariable analysis, psoriasis remained independently associated with lower IRRIV. Limitations: This was a single-center pilot study with a limited sample size. Conclusion: Moderate-to-severe psoriasis was associated with impaired renal functional reserve, suggesting subclinical renal microcirculatory dysfunction. Larger studies are needed to confirm these findings and define their clinical relevance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.