SynthesisFrontiers in nutrition2026
Effects of acute or short-term oral sodium bicarbonate supplementation on high-intensity intermittent exercise performance and physiological responses in team-sport athletes: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background: Sodium bicarbonate (NaHCO3) ingestion can induce extracellular alkalosis, but its effects on high-intensity intermittent exercise (HIIE) performance in team sports remain unclear. This study evaluated the effects of acute or short-term NaHCO3 ingestion on HIIE performance and physiological responses in team-sport athletes. Methods: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement. Six databases were searched from inception for randomized controlled trials, with the final search conducted on July 26, 2026. HIIE performance outcomes were synthesized using a covariance-adjusted three-level random-effects meta-analysis, whereas blood lactate, bicarbonate ( Results: Twenty studies involving 241 athletes contributed 53 performance effect sizes. NaHCO3 ingestion had a small beneficial effect on HIIE performance (Hedges' g = 0.23, 95% CI: 0.07 to 0.39, Conclusion: Acute or short-term NaHCO3 ingestion may provide a small average improvement in HIIE performance and increase post-exercise blood lactate, Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261424869, identifier: CRD420261424869.
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