ArticleResearch in heart yield and translational medicine2025
The Diagnostic Role of Speckle-Tracking Echocardiography-Derived Right Ventricular Longitudinal Strain in Determining the Severity of Rheumatic Mitral Stenosis.
Article in Research in heart yield and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highlights: 2D STE-derived RVGLS and RVFWLS associate with MS severity in patients with rheumatic MS.RVGLS have high sensitivity for ruling out severe MS during routine echocardiographic evaluation. Introduction: Echocardiographic planimetry is the primary and most available modality for diagnosing rheumatic mitral stenosis (MS). Nonetheless, this approach is highly reliant on the examiner's technique. Echocardiographic evaluation of MS should also include assessment of right ventricular (RV) function because of its prognostic role. We hypothesized that the assessment of RV function via speckle-tracking echocardiography could also have a diagnostic role in determining MS severity. Methods: This cross-sectional study included 47 patients with a typical diagnosis of rheumatic MS. Echocardiographic data were recorded and evaluated offline by an expert cardiologist. We measured right ventricular global longitudinal strain (RVGLS), right ventricular free-wall longitudinal strain (RVFWLS), mitral valve area (MVA) using 2D planimetry, and other conventional parameters of MS severity. Data were analyzed and visualized utilizing SPSS version 26 (IBM Corp) and Python 3.10.6 (Python Software Foundation). Results: Our analysis showed that both RVGLS (R=-0.598; P<0.05) and RVFWLS (R=-0.620; P<0.05) were significantly correlated with MVA. The mean RVGLS values in patients with severe and progressive MS were -14.44±4.36 and -18.12±3.25, respectively (P=0.017). The mean RVFWLS values also demonstrated a significant difference between these two groups (-6.3±4.7 vs-20.8±3.2; P=0.005). The area under the curve (AUC) for RVGLS and RVFWLS in detecting severe MS was 0.75 (95% CI, 0.64 to 0.86) and 0.78 (95% CI, 0.66 to 0.90), respectively. Conclusion: RVGLS and RVFWLS significantly correlate with MVA and may serve as tools to assess the severity of rheumatic MS in daily clinical practice. These strain parameters have high sensitivity for ruling out severe MS during routine echocardiographic evaluation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.