ArticleVeterinary evidence
Hypertonic saline versus Lactated Ringer's Solution for neurological recovery in cats with traumatic brain injury.
Article in Veterinary evidence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PICO question: In cats with traumatic brain injury, is hypertonic saline more effective than Lactated Ringer's Solution (LRS), when measuring neurological recovery?In dogs diagnosed with canine transmissible venereal tumour (CTVT), does treatment with vincristine combined with ivermectin, compared to treatment with vincristine alone, lead to improved clinical outcomes? Clinical bottom line: Category of research: Treatment. Number and type of study designs reviewed: Zero. Strength of evidence: Zero. Outcomes reported: Both hypertonic saline and LRS have been successfully used in the management of traumatic brain injuries in cats. There is not enough evidence to recommend one treatment over the other and they should be chosen with consideration of the individual after assessing patient status. Conclusion: In cats with traumatic brain injury, there is not enough evidence to say that hypertonic saline is more effective than LRS when measuring short-term neurological response with an improved Modified Glasgow Coma Score. How to apply this evidence in practice The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient's circumstances and owners' values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.