Evidence map›Paper›PMID 42781473›Full record

ArticleAJE advances : research in epidemiology2026

Place-based disorder, social cohesion, and physical and mental health outcomes of LGBTQIA+ adults in the United States.

Nguyen K Tran, David H Rehkopf, Charleigh Flohr, Juno Obedin-Maliver, Annesa Flentje, Mitchell R Lunn

Abstract read
In one paragraph

Article in AJE advances : research in epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nguyen K TranThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0002-5093-4499
David H RehkopfDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-7597-6513
Charleigh FlohrThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA.
Juno Obedin-MaliverThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0002-0945-2842
Annesa FlentjeThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0002-1964-4151
Mitchell R LunnThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0002-0068-0814

Funding

Mentoring the next generation of substance use, HIV, and epigenetic researchers in sexual and gender minority healthK24DA057874 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Annesa Flentje · 2023 to 2026
$793k
NIDA NIH HHS K24 DA057874
6 · The paper itself

Abstract

Place-based disorder and social cohesion may influence LGBTQIA+ adults' physical and mental health in meaningful ways given their heightened exposure to minority stress and discrimination. However, few studies have examined these associations. Using a sample of 3790 LGBTQIA+ adults in 786 counties from The Population Research in Identity and Disparities for Equality Study, we assessed associations of place-based disorder and social cohesion with depressive symptoms, perceived stress, and physical health using linear mixed models. We tested effect modification by gender modality and ethnoracial group. Residing in counties with higher social cohesion by 1-unit was associated with 1.06 lower points (95% CI -1.56, -0.56) for depressive symptoms, 1.60 lower points (95% CI -2.26, -0.94) for perceived stress, and 1.17 higher points (95% CI 0.43, 1.90) for physical health. Residence in counties with higher place-based disorder by 1-unit was only associated with 1.17 higher points (95% CI 0.32, 2.01) for perceived stress; no association was observed for depressive symptoms or physical health. We did not detect evidence of effect modification by ethnoracial groups, though association between place-based disorder and depressive symptoms appeared to differ by gender modality. Findings indicate that physical and social environments are important to the health of LGBTQIA+ individuals.

Indexed as

depressive symptomsLGBTQIA+ populationsmultilevel modelsperceived stressphysical healthplace-based disordersocial cohesionsocial determinants of health

Identifiers

PMID42781473
PMCPMC13599614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.