ArticleDEN open2027
Synchronous and Metachronous Multiple Gastric Epithelial Neoplasms Detected During Index Evaluation and Post-Endoscopic Submucosal Dissection Surveillance: A Descriptive Comparison.
Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objectives: We compared synchronous and metachronous gastric tumors detected during index evaluation and surveillance after endoscopic submucosal dissection (ESD), focusing on Kimura-Takemoto O-3 atrophy. Methods: We retrospectively reviewed consecutive patients who underwent ESD. Patients whose first additional lesion was detected simultaneously or within 1 year after index ESD were classified as having synchronous gastric tumors (SGT); those with no synchronous lesion whose first additional lesion was detected later were classified as having metachronous gastric tumors (MGT). Logistic regression estimated associations with SGT rather than MGT presentation. Results: Among 1064 screened patients, 256 had multiple lesions (SGT, Conclusions: O-3 atrophy was more frequent when the first additional lesion was detected synchronously. SGT and MGT may represent timing-defined phenotypes within a continuous atrophic field rather than biologically distinct entities. Extensive atrophy supports meticulous whole-stomach inspection at index evaluation and sustained surveillance.
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