ArticleJournal of inflammation research2026
Research Trends in Neutrophil Extracellular Traps and Ischemia-Reperfusion Injury: A Dual-Database Bibliometric Analysis from 2013 to 2025.
Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Neutrophil extracellular traps (NETs), defined as DNA-protein complexes released upon neutrophil activation, have been increasingly recognized as pivotal mediators in the initiation and perpetuation of ischemia-reperfusion injury (IRI) in recent scholarly investigations. Despite the increasing number of related studies, there is no bibliometric analysis in this field. This study aims to analyze the development trend, research status, and hotspots of NETs and IRI, thereby providing a comprehensive and intuitive academic reference for investigators in this field. Methods: The Web of Science Core Collection (WoSCC) database and Scopus database were used to search the literature in the field of NETs and IRI from January 1, 2013 to December 31, 2025. Using bibliometric software such as CiteSpace, VOSviewer, and the bibliometrix R-package, was used to conduct co-occurrence analysis, cluster analysis and emergence analysis were conducted on the annual number of publications, countries/regions, institutions, authors, journals and keywords. Results: This is the first bibliometric analysis systematically characterizing the landscape of NETs-mediated IRI research. After screening, 224 articles were used in the bibliometric analysis. These articles were from 449 institutions in 30 countries, written by 1642 authors, published in 141 journals, and cited 10326 times in total based on the merged dataset. The number of annual publications in this field is steadily but rapidly growing, with the United States, China, and Germany leading the way in research. Conclusion: The research on NETs and IRI is in a period of rapid development. Current studies have systematically elucidated the multiple pathogenic effects of NETs and IRI, and formed a research framework with "molecular mechanism-organ injury-inflammation regulation-intervention strategy" as the core. Bibliometric trends suggest that future research directions are likely to increasingly focus on the development of high-specificity inhibitors and clinical translational initiatives, as reflected by the increasing frequency of these topics in recent publications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.