Evidence map›Paper›PMID 42781106›Full record

ArticleCureus2026

Appendicitis on the Wrong Side: A Case of Left-Sided Acute Appendicitis With Intestinal Nonrotation.

Swathi Mulupuru, Srinidhi Srinivasan, Arun Paul, Lakshmi Chakradhar Yarlagadda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Swathi MulupuruEmergency Medicine, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, IND.
Srinidhi SrinivasanRadiology, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, IND.
Arun PaulRadiology, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, IND.
Lakshmi Chakradhar YarlagaddaInternal Medicine, GSL Medical College, Rajahmundry, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left-sided acute appendicitis (LSAA) is a rare clinical entity, most commonly associated with midgut malrotation (MM) or situs viscerum inversus (SVI). Its atypical presentation poses a significant diagnostic challenge for emergency physicians, radiologists, and surgeons. We report the case of a 53-year-old man who presented with a two-day history of left-sided abdominal pain, fever, and vomiting. Laboratory investigations revealed marked leukocytosis. Abdominal ultrasonography identified an appendix-like structure with surrounding inflammation in the left iliac fossa. Contrast-enhanced computed tomography (CT) of the abdomen confirmed midgut nonrotation, with the ascending colon positioned on the left side and an abnormal superior mesenteric artery-to-vein relationship. The patient underwent open appendectomy through a midline incision. Intraoperative findings confirmed LSAA with large bowel nonrotation. The postoperative course was complicated by peritonitis, which was managed with surgical intervention and broad-spectrum antibiotics. At the 21-day follow-up, the patient was asymptomatic. This case highlights the importance of maintaining a high index of suspicion for LSAA in patients presenting with atypical left lower quadrant pain. Thorough preoperative imaging, particularly CT, is essential for accurate diagnosis and operative planning. Prompt surgical management remains the cornerstone of treatment to prevent life-threatening complications.

Indexed as

acute abdomencase reportintestinal nonrotationleft-sided acute appendicitismidgut malrotationsuperior mesenteric artery

Identifiers

PMID42781106
PMCPMC13600141

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.