ArticleFASEB bioAdvances2026
Chiaki Yamada, Anny Ho, Natasha Sanz, Gang Peng, Ruijuan Xu, Cungui Mao, Xue Yuan, Fatemeh Momen-Heravi, Paul C Edwards, Frank Nichols and 1 more
Abstract read
In one paragraphArticle in FASEB bioAdvances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Chiaki YamadaDepartment of Biomedical and Applied Science Indiana University School of Dentistry Indianapolis Indiana USA.
Anny HoInstitute for Neuro-Immune Medicine Nova Southeastern University Fort Lauderdale Florida USA.
Natasha SanzDepartment of Biomedical and Applied Science Indiana University School of Dentistry Indianapolis Indiana USA.
Gang PengIndiana Center for Musculoskeletal Health Indiana University School of Medicine Indianapolis Indiana USA.
Ruijuan XuDepartment of Medicine, Stony Brook Cancer Center, Renaissance School of Medicine The State University of New York at Stony Brook Stony Brook New York USA.
Cungui MaoDepartment of Medicine, Stony Brook Cancer Center, Renaissance School of Medicine The State University of New York at Stony Brook Stony Brook New York USA.
Xue YuanDepartment of Otolaryngology-Head & Neck Surgery, School of Medicine Indiana University Indianapolis Indiana USA.
Fatemeh Momen-HeraviDepartment of Orofacial Sciences, School of Dentistry University of California San Francisco San Francisco California USA.
Paul C EdwardsDepartment of Oral Pathology, Medicine and Radiology Indiana University School of Dentistry Indianapolis Indiana USA.
Frank NicholsDepartment of Oral Health and Diagnostic Sciences University of Connecticut School of Dental Medicine Farmington Connecticut USA.
Funding
Immune and transcriptomic biomarkers of progressive oral premalignant lesionsU01DE033351 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Fatemeh Momen Heravi · 2023 to 2026
$3.1MSystems Biology and Multi-Omics Core (SBMO)P30AR083854 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI Matthew R Allen · 2024 to 2026
$2.8MSingle-cell RNA-sequencing for functional analysis of monocytes and macrophages in periodontitisR01DE032433 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Fatemeh Momen Heravi · 2024 to 2026
$1.9MImpact of Acid Ceramidase Activity on MIF-mediated migration of circulating osteoclast precursors to periodontal bone lesions in relation to agingR01AG064003 · NIA · NOVA SOUTHEASTERN UNIVERSITY · PI MOVILA, ALEXANDRU · 2019 to 2022
$1.8MThe biological mechanisms of racial disparity in head and neck cancerR01CA290401 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Fatemeh Momen Heravi · 2025 to 2026
$1.4MBLRD VA I21 BX006307NCI NIH HHS R01 CA290401NIAMS NIH HHS P30 AR083854NIA NIH HHS R01 AG064003NIDCR NIH HHS R01 DE032433NIDCR NIH HHS U01 DE033351
6 · The paper itselfAbstract
Intracellular sphingolipids play a complex role in the survival and migration of oral squamous cell carcinoma (OSCC). For instance, dihydroceramide and ceramide sphingolipids suppress proliferation, whereas sphingosine-1-phosphate (S-1-P) promotes it. The balance between ceramide/S-1-P is critically regulated by the ceramide-hydrolyzing enzyme, acid ceramidase (aCDase), in OSCC. Indeed, aCDase mRNA expression is significantly upregulated compared with that in healthy epithelial cells. Our group identified that
Indexed as
acid ceramidaseoral squamous cell carcinomaphosphoglycerol dihydroceramidePorphyromonas gingivalissphingolipids
Identifiers
PMID42781096
PMCPMC13599971
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