ArticleJournal of medical biochemistry2026
Plant-based superoxide dismutase supplementation in the athlete population.
Article in Journal of medical biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Physical exercise significantly influences the redox balance, with its intensity, duration, and type affecting the produc-tion of free radicals, including reactive oxygen and nitrogen species. An excess of free radicals can lead to oxidative stress. Elite athletes, due to rigorous training and often insufficient rest, are particularly susceptible to oxidative stress, which can negatively affect their health and sports performance. Plant-based superoxide dismutase (SOD), combined with gliadin isolated from wheat, is a relatively new dietary supplement known for its antioxidant proper-ties. The aim of this review was to evaluate the effects of SOD/gliadin supplementation among athletes. We exam-ined the impact of this supplementation on redox status, inflammatory markers, indicators of muscle damage, and sports performance. Overall, the analysis of the data indi-cated some beneficial effects on all observed aspects of athletes' health and performance. The effects of supple-mentation appear to depend on the type of sport, the ath-lete's training status, and the design of the supplementa-tion study. However, very few studies have been published on this topic; therefore, further research is needed to clarify the potential benefits of SOD/gliadin supplementation for athletes. Future studies should include a larger number of participants and implement controlled conditions with stan-dardised dosage regimens, enabling more robust, compa-rable, and reliable outcomes.
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