ArticleFrontiers in medicine2026
Clinical symptoms and prognosis of patients with pulmonary nodules: a real-world cohort study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Objective: To identify risk factors for pulmonary nodule progression based on a prospective cohort of 392 patients. Methods: Baseline clinical, imaging and quantitative indicators including volume doubling time (VDT) and fatigue scores were compared between patients with stable and progressive nodules. Univariate and multivariate Cox regression models were used to analyze prognostic factors. Results: Among all subjects, 61.0% had COVID-19 infection history, and 33.7% of nodules presented lobulation and spiculation. During follow-up, 25.2% of nodules progressed, and the progression group had shorter VDT and higher fatigue scores ( Conclusion: Age, smoking status and high-risk imaging features predict nodule progression. Risk-stratified follow-up should be performed for high-risk populations.
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