Evidence map›Paper›PMID 42780728›Full record

ArticleFrontiers in cell and developmental biology2026

Integrated RNA-seq and ATAC-seq analyses reveal muscle development differences between european meat pigeon and shiqi pigeon during embryonic to post-hatching stages.

Yuanhao Han, Pufei Hong, Ziyang Liu, Tiande Chen, Kaiyue Chang, Weifeng Chen, Yirou Zhong, Ziyi Qiu, Zhihao Zheng, Xiujin Li and 3 more

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In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Yuanhao HanCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Pufei HongCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Ziyang LiuCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Tiande ChenCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Kaiyue ChangCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Weifeng ChenCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Yirou ZhongCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Ziyi QiuCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Zhihao ZhengCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Xiujin LiCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Zhongping WuCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Yayan LiangCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Xumeng ZhangCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poultry muscle growth and development critically depend on skeletal muscle formation during embryonic and hatching stages. However, early embryonic muscle development differences between pigeon breeds remain unclear. We used European meat pigeons and Shiqi pigeons, which differ in body size, as models. Pectoral muscles from both breeds were subjected to ATAC-seq and RNA-seq at embryonic day 14 (E14) and post-hatching day 1 (P1). At P1, Shiqi pigeons had a significantly greater proportion of myofibers with 1-50 μm diameters, higher myofiber density, and a predominant 50-100 μm distribution across developmental stages compared to European meat pigeons. Integrated ATAC-seq and RNA-seq analyses revealed developmental dynamics driven by muscle contraction, cardiac regulatory pathways, and PI3K-Akt/muscle remodeling signaling, as well as breed differences in chromosomal structure/cell cycle regulation, cancer-related pathways, metabolic homeostasis, and calcium/estrogen signaling. Furthermore, 62 chromatin accessibility-gene expression co-varying DEGs (59 upregulated) were enriched in insulin receptor binding and AMPK/cGMP-PKG pathways; key genes including

Indexed as

ATAC-seqembryonic pectoral muscle developmenteuropean meat pigeonRNA-seqshiqi pigeon

Identifiers

PMID42780728
PMCPMC13597791

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